It is assumed that the user will be initiating the applications from a terminal window, as under Unix/Linux. The directories containing the program binaries (/usr/local/xictools/bin) and the bundle programs (/usr/local/gtk2-bundle-x11/bin) should be in the shell search path. Then, all executables will be found by name. Operation is the same as under Unix/Linux.
The X-Windows server must be running for successful execution of the programs that use graphics. In OS X Mavericks the Apple "XQuartz" X-server will start automatically when needed (remember that this must be downloaded, as it is not installed automatically in Mavericks), however this causes the initial program startup time to be rather long.